Endocrine Abstracts

Introduction: The signaling involved in ligand-stimulated spermatozoa is not yet clarified. Moreover, the main question in sperm biology is the identification of the sperm ligands. Analysis of the role of MAPK in mammalian sperm physiology is a prerequisite for assigning a role for MAPK in mammalian sperm functions. The unique opportunity to study ERK1/2 in human spermatozoa, which are differentiated cells lacking active transcriptional machinery, will enable to correlate it t...